Identifikasi Keragaman Genetik Gen Inhibin Subunit Alpha (INHA) dan Inhibin Subunit Beta A (INHBA) Pada Sapi Peranakan Ongole (PO)
DOI:
https://doi.org/10.21776/ub.jtapro.2021.022.01.9Keywords:
Keragaman, gen INHA, gen INHBA, pertumbuhan, sapi POAbstract
Gen Inhibin berperan dalam mengatur proliferasi sel, pertumbuhan kelenjar adrenal, hematopoiesis dan metabolisme tulang. Inhibin subunit alpha juga diketahui memiliki dampak yang signifikan terhadap berat badan, panjang tubuh dan lingkar badan. Penelitian ini bertujuan untuk mengidentifikasi keragaman gen INHA dan INHBA pada Sapi PO yang berturut-turut sebanyak 68 ekor sapi PO yang berasal dari UPT PT HMT Tuban dan 11 ekor sapi PO BBIB Singosari. Metode pendeteksian keragaman gen menggunakan metode sequencing. Hasil penelitian menunjukkan bahwa pada sapi PO populasi UPT Tuban ditemukan tiga genotipe (AA, AB dan BB) pada fragmen gen INHA dan INHBA, sapi PO populasi BBIB Singosari memiliki satu genotipe (AA) pada fragmen gen INHA serta dua genotipe (AA dan BB) pada fragmen gen INHBA. Berdasarkan hasil tersebut dapat disimpulkan bahwa gen INHA dan INHBA pada sapi PO populasi UPT Tuban dalam kondisi beragam (polimorfik). Informasi dalam penelitian ini dapat dijadikan dasar atau landasan dalam memulai program seleksi dan perkawinan sapi potong lokal Indonesia berbasis teknologi molekuler.
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